An International Journal for Oncology Research.  

 


December 2008
Volume 10, Number 12
Cover Illustration:
The cover artistically depicts the results from the paper by Michael et.al. demonstrating a role for Bmi-1 in hedgehog driven medulloblastoma expansion

TABLE OF CONTENTS

Research Article

A mammary-specific, long-range deletion on mouse chromosome 11 accelerates Brca1-associated mammary tumorigenesis
Aleata A. Triplett, Cristina Montagna and Kay-Uwe Wagner
Abstract   Full Article

Insulin-like growth factor binding protein 7 (IGFBP-7) mediates glioma cell growth and migration
Wei Jiang, Cunli Xiang, Simona Cazacu, Chaya Brodie and Tom Mikkelsen
Abstract   Full Article

Bmi1 is required for Hedgehog-pathway driven medulloblastoma expansion
Lowell E Michael, Bart A Westerman, Alexandre N Ermilov, Aiqin Wang, Jennifer Ferris, Jianhong Liu, Marleen Blom, David W Ellison, Maarten van Lohuizen and Andrzej Dlugosz
Abstract   Full Article

Senescence-induced alterations of laminin chain expression modulate tumorigenicity of prostate cancer cells
Cynthia C. T. Sprenger, Rolf H Drivdahl, Lillie B Woodke, Daniel Eyman, May J Reed, William G Carter and Stephen Plymate
Abstract   Full Article

Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations
Navneet Sangha, rong wu, Rork Kuick, Scott Powers, David Mu, Diane Fiander, Kit Yuen, Hidetaka Katabuchi, Hironori Tashiro, Eric R Fearon and Kathleen R. Cho
Abstract   Full Article

Tumor progression and oncogene addiction in a PDGF-B-induced model of gliomagenesis
Filippo Calzolari, Irene Appolloni, Evelina Tutucci, Sara Caviglia, Marta Terrile, Giorgio Corte and Paolo Malatesta
Abstract   Full Article

Combining bevacizumab with temozolomide increases the anti-tumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model
Veronique Mathieu, Nancy De Nève, Marie Le Mercier, Janique Dewelle, Jean-François Gaussin, Mischael Dehoux, Robert Kiss and Florence Lefranc
Abstract   Full Article

Src family kinases mediate betel quid-induced oral cancer cell motility and could be a biomarker for early invasion in oral squamous cell carcinoma
Jeff Yi-Fu Chen, Chih-Chang Hung, Kai-Lieh Huang, Yi-Ting Chen, Shyun-Yeu Liu, Wei-Fan Chiang, Hau-Ren Chen, Ching-Yu Yen, Yu-Jen Wu, Jeng-Yuh Ko and Yuh-Shan Jou
Abstract   Full Article

Resistance of cytarabine induces the up-regulation of NKG2D ligands and enhances natural killer cell lysis of leukemic cells
Henry Ogbomo, Martin Michaelis, Denise Klassert, Hans W Doerr and Jindrich Cinatl
Abstract   Full Article

Slit2 inhibits the growth and metastasis of fibrosarcoma and squamous cell carcinoma
Hee Kyung Kim, Hong Zhang, Hui Li, Tsung-Teh Wu, Stephen Swisher, Donggou He, Lizhi Wu, Jianmin Xu, Craig A Elmets, mohammad Athar, Xiaochun Xu and Hui Xu
Abstract   Full Article

Phorbol ester enhances KAI1 transcription by recruiting Tip60/Pontin complexes
Alexandra Rowe, Jorg Weiske, Tobias S Kramer, Otmar Huber and Paul Jackson
Abstract   Full Article

Sca-1 identifies the tumor initiating cells in mammary tumors of BALB-NEUT transgenic mice.
Cristina Grange, Stefania Lanzardo, Federica Cavallo, giovanni camussi and Benedetta Bussolati
Abstract   Full Article

Restoration of E-cadherin cell-cell junctions requires both expression of E-cadherin and suppression of ERK MAP kinase activation in Ras-transformed breast epithelial cells
Quanwen Li and Raymond R Mattingly
Abstract   Full Article

Improved MR molecular imaging of tumor angiogenesis by avidin-induced clearance of non-bound bimodal liposomes
Geralda A.F. van Tilborg, Willem J. M. Mulder, Daisy W.J. van der Schaft, Chris P.M. Reutelingsperger, Arjan W. Griffioen, Gustav J Strijkers and Klaas Nicolay
Abstract   Full Article

WNT5A is regulated by PAX2 and may be involved in blastemal predominant wilms tumorigenesis
Yahya Tamimi, Usukuma Ekuere, Nicholas Laughton and Paul Grundy
Abstract   Full Article

The variant HNF1 modulates epithelial plasticity of normal and transformed ovary cells
Antonella Tomassetti, Giuseppina De Santis, Giancarlo Castellano, Silvia Miotti, Mimma Mazzi, Daniela Tomasoni, Frans Van Roy, Maria L Carcangiu and Silvana Canevari
Abstract   Full Article

Review Article

Neoplasia: The second decade
Alnawaz Rehemtulla
Abstract   Full Article

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